Obesity and natriuretic peptides, BNP and NT-proBNP: Mechanisms and diagnostic implications for heart failure
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منابع مشابه
Obesity and natriuretic peptides, BNP and NT-proBNP: mechanisms and diagnostic implications for heart failure.
Many advances have been made in the diagnosis and management of heart failure (HF) in recent years. Cardiac biomarkers are an essential tool for clinicians: point of care B-type natriuretic peptide (BNP) and its N-terminal counterpart (NT-proBNP) levels help distinguish cardiac from non-cardiac causes of dyspnea and are also useful in the prognosis and monitoring of the efficacy of therapy. One...
متن کاملNatriuretic peptides (BNP and NT-proBNP): measurement and relevance in heart failure
For patients presenting with acute dyspnea, an incorrect diagnosis could increase the mortality risk. When used in the evaluation of patients with acute symptoms, brain natriuretic peptide and N-terminal pro-brain natriuretic peptide (BNP and NT-proBNP, respectively) testing is highly sensitive for the diagnosis or exclusion of acute or chronic decompensated heart failure (HF). It has been demo...
متن کاملHuman ProBNP and proBNP-derived Peptides (BNP and NT-proBNP)
Brain natriuretic peptide (BNP) is a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties (1, 2, 3). BNP belongs to a family of structurally similar peptide hormones that also includes atrial natriuretic peptide (ANP), C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a 17 amino acid ring structure with a disulfide bond between two cy...
متن کاملComparison of the diagnostic accuracy of BNP and NT-proBNP in acute and chronic heart failure.
when the infant was 18 months old, and again this sample showed evidence of significant hemolysis, with decreased hemoglobin (60 g/L), hematocrit (0.18), and erythrocyte count (2.4 10). The normochromic blood film showed pencil cells, some elliptocytes, and erythrocyte fragments. Mass spectrometry confirmed a complete switch to an adult pattern of hemoglobin synthesis, with no significant amoun...
متن کاملDiagnostic and prognostic values of B-type natriuretic peptides (BNP) and N-terminal fragment brain natriuretic peptides (NT-pro-BNP)
B-type natriuretic peptide (BNP) is a member of a fournatriuretic peptide family that shares a common 17-peptide ring structure. The N-terminal fragment (NT-pro-BNP) is biologically inert, but both are secreted in the plasma in equimolar quantities and both have been evaluated for use in the management of congestive heart failure. BNP and NT-pro-BNP are frequently used in the diagnosis of conge...
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ژورنال
عنوان ژورنال: International Journal of Cardiology
سال: 2014
ISSN: 0167-5273
DOI: 10.1016/j.ijcard.2014.08.007